New data shows Telomir-1 fully reverses STAT1 gene silencing by DNA methylation – a key immune regulator suppressed in cancer – delivering stronger epigenetic effects than Paclitaxel or Rapamycin in ...
Researchers from Tokyo Medical and Dental University (TMDU) find three novel variants in STAT1 that cause Mendelian susceptibility to mycobacterial disease Tokyo, Japan – Usually, the scariest part of ...
In summary, macrophages secrete IFN-β, activating the IFN-β-IFNAR-p-STAT1 axis in MICFs, leading to increased secretion of CCL2/7/12 chemokines and subsequent recruitment of more IFN-β-secreting ...