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Super-enhancers: Cancer's double-edged sword of growth and DNA damage
New study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...
Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601 Sequencing data from 56,965 ...
Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive ...
Researchers found that brief intense workouts enhance DNA repair in colon cancer cells by altering proteins circulating in the bloodstream ...
Identification of variants influences treatment decisions. Inhibitors of the poly-ADP-ribose polymerase (PARP) system, a pathway for repairing single-stranded DNA breaks, are recommended for tumors ...
When starting a New Year fitness routine, take heart that a new study shows that 10 minutes of intense exercise could help ...
Cars patched up after a wreck may look fixed—but never run quite as before. The same may hold true for chromatin, according to a study published in Science on November 6. In response to double-strand ...
The DNA of human cells consists of a sequence of about 3.1 billion building blocks. Cells go to great lengths to maintain the integrity of this vast store of information. They constantly untangle ...
Experimental gene therapies like AMT‑130 lower toxic huntingtin protein and significantly slow Huntington’s disease, offering ...
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