A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as ...

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

The mitochondrial genome of Trypanosoma brucei is uniquely organised as a kinetoplast, a highly complex network composed of thousands of minicircles and a smaller number of maxicircles. This structure ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

The artificial cell nucleus (right) constructed using the purified DNA was morphologically very similar to the natural cell nucleus derived from an egg (left). A team led by Professor Kazuo Yamagata ...